BIO 463 : Genetics of Human Disease.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | PWS 340 |
| DESCRIPTION:  | Examining the application of genetics to understanding and treatment of human disease. Functional consequences of mutations; use of model organisms; linkage and association analysis of complex traits; pharmacogenetics; ethical considerations. |
BIO 465 : Bioinformatics and Proteomics.
(3:2:1)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | BIO 365 |
| DESCRIPTION:  | 3-D protein structural comparisons, hidden Markov models for database comparisons, homology detection, multiple sequence analyses, and protein family comparisons. Exercises in computer programming in genomics. |
CHEM 463 : Physical Chemistry.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | CHEM 227 & CHEM 462 & PHSCS 123 & MATH 302; or CHEM 227 & CHEM 462 & PHSCS 123 & MATH 314 |
| RECOMMENDED: | Math 302. |
| DESCRIPTION:  | Thermodynamics and equilibria, states of matter, kinetic-molecular theory, kinetics, statistical mechanics. |
CHEM 468 : Biophysical Chemistry.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | CHEM 481 & MATH 113 & PHSCS 123; or CHEM 481M & MATH 113 & PHSCS 123 |
| DESCRIPTION:  | Applications of physical chemistry to biological systems. Spectroscopic applications, computational methods, structural biochemistry, thermodynamics, equilibria, statistical mechanics, transport properties, kinetics, quantum mechanics. |
| NOTE: | For biochemistry (BS) majors and those interested in the health professions or biochemistry. |
CHEM 482 : Mechanisms of Molecular Biology.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | CHEM 481M; or CHEM 481 |
| DESCRIPTION:  | Second-semester biochemistry. Nucleic acid biochemistry and molecular biology: nucleotide metabolism, chromosome and chromatin structure, DNA structure and replication, RNA transcription and gene expression, protein synthesis and regulation, eukaryotic gene systems, signal transduction. |
CHEM 581 : Advanced Biochemical Methodology 1.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall |
| PREREQUISITE: | Chem 482 or equivalent. |
| DESCRIPTION:  | Analytical and structural determination methods used in biochemical research, including mass spectrometry-based proteomics, immunotechniques, atomic force and electron microscopy, NMR and X-ray diffraction. |
| NOTE: | One of two required courses for biochemistry graduate students. May be taken before or after Chem 583. |
CHEM 584 : Biochemistry Laboratory/Proteins.
(3:1:6)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter |
| PREREQUISITE: | CHEM 481M; or CHEM 481; or equivalent. |
| DESCRIPTION:  | Introduction to current biochemical research procedures including spectrophotometry, chromatography, electrophoresis, and immunological techniques. Protein over-expression; isolation and characterization methods. Enzyme kinetics and protein-ligand interactions. Introduction to bioinformatics. |
| NOTE: | May be taken before or after Chem 586. |
CHEM 586 : Biochemistry Laboratory/Nucleic Acids.
(3:1:6)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter |
| PREREQUISITE: | CHEM 482 |
| DESCRIPTION:  | Laboratory course covering major techniques involved in isolation, amplification, and cloning of recombinant DNA as well as isolation, synthesis, translation, and identification of RNA. |
| NOTE: | May be taken before or after Chem 584. |
MMBIO 151 : Introduction to Microbiology.
(4:3:3)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter; Summer |
| PREREQUISITE: | Chem 105 or concurrent enrollment. |
| DESCRIPTION:  | Principles of prokaryotic biology emphasizing cell structure, function, and metabolism. Introduction to bacterial genetics, microbial diversity, and microbial ecology. |
MMBIO 194A : Freshman Research Initiative 1.
(2:0:6)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall |
| PREREQUISITE: | By application only. |
| DESCRIPTION:  | Phage isolation and characterization. |
| NOTE: | For freshmen or sophomore students only. Requires two semester commitment. |
MMBIO 194B : Freshman Research Initiative 2.
(2:0:6)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | MMBIO 194A |
| DESCRIPTION:  | Phage genome annotation. Focus on experimental design and data analysis. |
| NOTE: | For freshmen or sophomore students only. Requires two semester commitment. |
MMBIO 261 : Infection and Immunity.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter; Spring |
| DESCRIPTION:  | Principles of infectious organisms (principally bacteria and viruses), the diseases they cause, and the role of host immune responses in health and disease. |
MMBIO 360 : Microbial Genetics.
(4:3:3)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall |
| PREREQUISITE: | MMBIO 240 |
| DESCRIPTION:  | How DNA governs complex bacterial functions. Classical and modern approaches to gene discovery, including genetic screens, gene mapping, targeted genetic manipulations, and analyzing gene activity. |
MMBIO 364 : Bacterial Pathogenesis.
(4:3:3)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | MMBIO 261 |
| DESCRIPTION:  | Fundamental principles of bacterial pathogenesis, emphasizing the molecular interactions of medically important bacteria and their hosts. |
MMBIO 465 : Virology.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter |
| PREREQUISITE: | MMBio 261 or equivalent. |
| DESCRIPTION:  | Basic principles of virology, emphasizing selected molecular aspects of virus life cycles and disease processes. |
MMBIO 466 : Virology Laboratory.
(1:0:3)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | MMBio 261; or MMBio 465 or concurrent enrollment. |
| DESCRIPTION:  | Laboratory exercises illustrating in vitro behavior of selected viruses. Developing laboratory skills for virus studies. |
MMBIO 467 : Immunology Lab.
(1:0:3)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall |
| PREREQUISITE: | MMBio 261; or 463 or concurrent enrollment. |
| DESCRIPTION:  | Laboratory exercises in advanced concepts of immunological processes. |
MMBIO 510 : History of Microbiology and Molecular Biology.
(2:2:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter Even Yrs. |
| PREREQUISITE: | Any one 400-level MMBio course. |
| DESCRIPTION:  | Exploring the lives and historical settings of major contributors to the development of the sciences of microbiology and molecular biology emphasizing the importance of their ground-breaking discoveries in both basic and applied science. |
MMBIO 513 : Philosophy of Biology.
(2:2:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall Even Yrs. |
| PREREQUISITE: | MMBio 360 or 363 or 461 or equivalent. |
| DESCRIPTION:  | Epistemological, metaphysical, and ethical issues in the biological sciences. Philosophical questions concerning the theory of evolution, debate between evolution and creationism, fitness, adaptationism, the units of selection, systematics, sociobiology, and evolutionary ethics. |
MMBIO 515 : RNA-Mediated Gene Regulation.
(2:2:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall Odd Yrs. |
| PREREQUISITE: | MMBio 441 or equivalent. |
| DESCRIPTION:  | Current advances in studies on RNA processing, including RNA splicing and editing, riboswitches, ribozymes, and the role of small RNAs in RNA interference and regulation of gene expression. |
MMBIO 557 : Genes and Cancer.
(2:2:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter Odd Yrs. |
| PREREQUISITE: | MMBio 441 or equivalent. |
| DESCRIPTION:  | Molecular basis of human cancers, emphasizing oncogenes, tumor suppressor genes, chromosomal instability, hereditary cancers, chemical and physical carcinogens, and viral carcinogenesis. |
MMBIO 565 : Molecular Virology.
(2:2:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter Odd Yrs. |
| PREREQUISITE: | MMBio 465 or equivalent. |
| DESCRIPTION:  | Molecular mechanisms of virus architecture, attachment and entry pathways, replication strategies, oncogenesis, evolution, and mechanisms of pathogenesis. |
PDBIO 362 : Advanced Physiology.
(3:3:1)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter; Spring |
| PREREQUISITE: | MMBIO 240 & PHSCS 106; or MMBIO 240 & PHSCS 220 |
| DESCRIPTION:  | Integrated approach to organ system and cellular physiology. Problem solving/calculations. |
| NOTE: | Requires background in chemistry and molecular biology. Students without this background should take PDBio 305. |
PDBIO 363 : Advanced Physiology Laboratory.
(1:.5:1.5)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter; Spring |
| PREREQUISITE: | PDBio 362 or concurrent enrollment; or instructor's consent. |
| DESCRIPTION:  | Experiments and exercises in advanced physiology emphasizing human physiology. Computer simulations of muscle function, endocrine disease, and human physiology. Emphasizes problem solving and calculations. |
PDBIO 482 : Developmental Biology.
(3:3:1)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Fall; Winter |
| PREREQUISITE: | MMBIO 240 & MMBIO 241 & PDBIO 360 |
| RECOMMENDED: | PDBio 325. |
| DESCRIPTION:  | Invertebrate and vertebrate developmental biology. Embryonic gastrulation, neurulation, pattering, etc. Modern approaches and research strategies. Emphasizes gene function, cell signaling, signal transduction during embryogenesis. |
PDBIO 582 : Developmental Genetics.
(3:3:0)(Credit Hours:Lecture Hours:Lab Hours)| WHEN TAUGHT: | Winter |
| PREREQUISITE: | PDBio 482 or equivalent. |
| DESCRIPTION:  | Gene function and regulation during cell specification and differentiation, pattern formation, and organogenesis in developing embryo. |
Note 1: Only 3 hours of MMBio 399R will count toward major hours.
Note 2: indicates a course with a lab included.