UNDERGRADUATE CATALOG 2002–2003
Brigham Young University
Back Microbiology

   

Alan R. Harker, Chair
775 WIDB, (801) 422-2889

College of Biology and Agriculture Advisement Center
380 WIDB, (801) 422-3042

Admission to Degree Program

All degree programs in the Department of Microbiology are open enrollment. However, special limitations apply for clinical laboratory science and teaching majors.

The Discipline

The Microbiology Department offers programs leading to specialization in immunology, virology, medical microbiology, microbial genetics, microbial physiology, clinical laboratory science, environmental and industrial microbiology, general microbiology, molecular forensic science, molecular cytogenetics, and diagnostic molecular genetics.

Career Opportunities

Graduates are employed in a wide variety of positions in industry, hospitals, government agencies, and universities. Microbiology is an excellent preprofessional course of study for those interested in medicine, dentistry, law, or business.

Graduation Requirements

To receive a bachelor's degree a student must fill three groups of requirements: (1) general education requirements; (2) university requirements; and (3) major requirements.

General Education Requirements

Students should contact their college advisement center for information about general education courses that will also fill major requirements.

Languages of Learning

Precollege Math (zero to one course)
(or Math ACT score of at least 22)
0–3.0 hours
First-Year Writing (one course) 3.0
Advanced Writing (one course) 3.0
Advanced Languages/Math/Music
(one to four courses)
3–20.0

Liberal Arts Core

Biological Science (one to two courses) 3–6.0
Physical Science (one to two courses) 3–7.0
American Heritage (one to two courses) 3–6.0
Wellness (one to three courses) 1.5–2.0
Civilization (two courses) 6.0

Arts and Sciences Electives

Arts and Letters (one course) 3.0
Natural Sciences (one course) 3–4.0
Social and Behavioral Sciences (one course) 3.0

Note 1: For a complete list of courses that will fill each GE category, see the General Education section of the current class schedule.

Note 2: Additional information about general education requirements can be found in the General Education section of the current class schedule or this catalog.

Minimum University Requirements

Religion 14.0
Residency 30.0
Hours needed to graduate 120.0

Cumulative GPA must be at least 2.0.

Note: See the Graduation section of this catalog for more information.

Major Requirements

Complete the major requirements listed under one of the following undergraduate degree programs.

Undergraduate Programs and Degrees

BS Microbiology
BS Biology Composite Teaching
BS Clinical Laboratory Science
Emphasis (optional)
Diagnostic Molecular Genetics
Minor Microbiology

Students should see their faculty advisor for help or information concerning the undergraduate programs.

Note: For the molecular biology program, see the Molecular Biology section of this catalog. The molecular biology minor couples effective with certain majors or options in this department.

Graduate Programs and Degrees

MS Microbiology
PhD Microbiology

For more information see the BYU 2002–2003 Graduate Catalog.



BS Microbiology (63 hours*)

This is the preferred degree for microbiology majors who desire an advanced degree (master's or doctorate) in microbiology.

Major Requirements

  1. No more than 5 hours of D credit in required supporting courses and no grades lower than C– in microbiology will be accepted for graduation.

  2. Students must complete a minimum of 12 credits in microbiology courses numbered 400 or higher while in residence.

  3. Complete the following core requirements:
    Mcbio 101, 130, 230, 265, 291, 330, 351, 365, 465, 481.

  4. Complete at least 12 hours from the following:
    Mcbio 371, 402, 403, 404, 417, 418, 423, 425, 430, 451, 471.
    Mcbio 441 or MolB 480.
    Mcbio 442 or MolB 488.

  5. Complete the following:
    Chem 105, 106, 107, 351, 352, 481.
    Math 119 (or equivalent).
    Phscs 105, 106, 107, 108.

  6. Complete 1 hour of the following:
    Chem 353.

Note: Students desiring a minor in chemistry must take Chem 223.

*Hours include courses that may fulfill GE or university requirements.



BS Biology Composite Teaching (93–97 hours,* including licensure hours)

Major Requirements

  1. No D credit is allowed in the major, and no more than 5 hours of D credit is allowed in required supporting courses.

  2. Complete the following:
    Mcbio 130.
    Botny 105, 205, 475.
    Zool 204, 276, 338, 344, 350, 355, 493.

  3. Complete one of the following options:
    Either Chem 101, 152, 281
    Or Chem 105, 106, 107, 351.

  4. Complete the following:
    Geol 101.
    Math 110 (or equivalent).
    Phscs 105, 106.

  5. Complete the following:
    Mcbio 230, 265, 351, 402.

  6. Complete the Professional Education Component (28–29 hours). See the Secondary Education section of this catalog for licensure requirements.

Recommended Courses:

AgHrt 282, 283.
Botny 120, 210, 321, 331, 332, 480, 527.
Mcbio 311.
Range 225, 565.
Zool 134, 312, 317, 330, 350, 380, 445, 446, 447, 460, 561.
Geol 103, 111, 112.
Math 111, 119.

*Hours include courses that may fulfill GE or university requirements.



BS Clinical Laboratory Science (72 hours*)

This is a limited-enrollment program requiring departmental admissions approval. Please see the department office for information regarding requirements for admission to this major. Premajor Program MAP

This degree is for students who desire to practice medical technology in diagnostic laboratories or related options. The curriculum in clinical laboratory science is accredited by the National Accrediting Agency for Clinical Laboratory Sciences (8410 West Bryn Mawr Avenue, Suite 670, Chicago, IL [773] 714-8880).

Major Requirements

  1. No more than 5 hours of D credit in required supporting courses and no grades lower than a C– in microbiology will be accepted for graduation.

  2. Students must complete a minimum of 12 credits in microbiology courses numbered 400 or higher while in residence.

  3. Complete the following:
    Mcbio 102, 130, 230, 265, 330, 351, 392, 393, 394, 395, 402, 403, 407, 417, 418, 420, 421, 491R.

  4. During one semester and one term, complete at least 2 hours from the following:
    Mcbio 399R.

  5. Complete the following:
    Chem 105, 106, 107, 152, 281.
    Math 119 (or equivalent).
    Phscs 105, 106.

Recommended Courses

Mcbio 410, 411, 412, 413.
Stat 221.

*Hours include courses that may fulfill GE or university requirements.



BS Clinical Laboratory Science: Diagnostic Molecular Genetics Emphasis (68 hours)

Major Requirements

  1. No more than 5 hours of D credit in required supporting courses and no grades lower than a C– in microbiology will be accepted for graduation.

  2. Students must complete a minimum 12 credits in microbiology courses numbered 400 or higher while in residence.

  3. Complete the following:
    Mcbio 130, 230, 265, 291, 330, 351, 365, 392, 393, 402, 410, 411, 412, 413.

  4. Complete one course from the following:
    Mcbio 441.
    MolB 480.

  5. Complete one course from the following:
    Mcbio 442.
    MolB 488.

  6. Complete at least 2 hours from the following:
    Mcbio 495R.

  7. Complete the following:
    Chem 105, 106, 107, 152, 281.
    Math 119 (or equivalent).
    Phscs 105, 106.
    Stat 221.

Recommended Courses

Mcbio 394, 395, 420, 421.
Phscs 107, 108.

*Hours include courses that may fulfill GE or university requirements.



Minor Microbiology (16 hours)

Minor Requirements

  1. Complete the following:
    Mcbio 130, 230, 330, 351, 481.

  2. Complete one course from the following:
    Mcbio 371, 402, 403, 404, 425.



Microbiology (Mcbio)

Class Schedule Major Academic Plan (MAP)

Undergraduate Courses

101. Survey of Research Interests in Microbiology. (1:1:0)

Introduction of faculty and their research interests.

102. Introduction to Clinical Laboratory Techniques. (1:0:3)

Hospital laboratory techniques.

130. General Biology. (3:3:0) Prerequisite: concurrent enrollment in Chem 105.

Biological principles, including subcellular and cellular biology. For department majors.

221. General Microbiology. (3:3:0) Independent Study also. Honors also. Prerequisite: any chemistry course and any biology course.

Microbial world, emphasizing communicable diseases, their causes, and control. Recommended for students seeking a liberal education in microbiology who do not have the prerequisites to take the more advanced courses.

222. General Microbiology Laboratory. (1:0:2) Prerequisite: Mcbio 221 or concurrent enrollment.

230. General and Molecular Genetics. (3:3:0) Prerequisite: Mcbio 130.

General genetics and molecular biology of cell structure and function.

265. Laboratory Methods. (2:0:6) Prerequisite: Mcbio 130, Chem 105, 107, or equivalents.

Introduction to laboratory methodology used in microbiology, immunology, and molecular biology.

291. Readings in Science. (1:1:0) Prerequisite: Mcbio 130 or equivalent.

Introduction to scientific literature, library methods in science, and literature search techniques.

311. Disease and Public Health. (3:3:0)

A philosophical introduction to science of microbiology. Roles of individual and community in maintaining a healthful environment.

330. Biology of Integrated Systems. (3:3:0) Prerequisite: Mcbio 230.

Emphasizes biology of integrated systems, including ecology, evolution, cellular organelle function, disease, and symbiosis.

351. Microbiology. (3:3:0) Prerequisite: Mcbio 291, 330.

Introductory principles and applications of microbiology for majors.

365. Intermediate Laboratory Methods. (2:0:6) Prerequisite: Mcbio 265 and 351.

Experimental methodology in bacteriology. Investigative approach to experimental microbiology.

371. Microbial Ecology. (3:3:0) Prerequisite: Mcbio 351.

Principles of prokaryotic ecology. Microbial communities in their natural habitats, role of microorganisms in biogeochemical cycling.

392. Hematology. (2.5:2.5:0) Prerequisite: clinical laboratory science program acceptance.

Normal and abnormal hematology.

393. Immunohematology and Coagulation Theory. (2.5:2.5:0) Prerequisite: clinical laboratory science program acceptance.

Theory and practice of bloodbanking and coagulation theory.

394. Practical Hematology. (2:0:6) Prerequisite: Mcbio 392 or concurrent enrollment.

Laboratory to accompany Mcbio 392; emphasizes medical laboratory techniques in hematology.

395. Practical Immunohematology and Coagulation Theory. (2:0:6) Prerequisite: Mcbio 393 or concurrent enrollment.

Laboratory to accompany Mcbio 393; medical laboratory techniques in immunohematology and coagulation theory.

399R. Academic Internship: Clinical Laboratory Experience. (1–9:0:40 ea.)

402. Biology of the Immune System. (3:3:0) Prerequisite: Mcbio 351.

Fundamentals of immune mechanisms.

403. Medical Microbiology. (3:3:0) Prerequisite: Mcbio 351.

Introduction to infectious diseases.

404. General Animal Virology. (3:3:0) Prerequisite: Mcbio 351.

Basic principles of animal and medical virology.

407. Clinical Microbiology. (4:2:6) Prerequisite: Mcbio 403.

Approaches to laboratory diagnosis of infectious diseases.

410. Molecular Biomethodologies. (3:3:0) Prerequisite: Mcbio 365 or equivalent.

Basic molecular biomethodologies.

411. Molecular Biomethodologies Lab. (2:0:6) Prerequisite: concurrent enrollment in Mcbio 410.

Techniques utilized in diagnostic molecular laboratories.

412. Molecular Cytogenetics. (3:3:0) Prerequisite: Mcbio 365 or equivalent.

Pedigree analysis, genetic testing, and various genetic disorders.

413. Molecular Cytogenetic Laboratory. (2:0:6) Prerequisite: concurrent enrollment in Mcbio 412.

Laboratory methods in molecular cytogenetics.

417. (Micro-Zool) Medical Parasitology. (2:2:0) Prerequisite: Biol 100 or equivalent.

Pathogenesis, diagnosis, and epidemiology of human parasitic diseases.

418. (Mcbio-Zool) Parasitology Laboratory. (1:0:3) Prerequisite: Mcbio-Zool 417 or concurrent enrollment.

Diagnostic techniques of human parasitic infections.

420. Pathophysiology and Laboratory Diagnosis in Clinical Chemistry and Urinalysis. (5:5:0) Prerequisite: clinical laboratory science program acceptance.

Medical laboratory techniques in urinalysis, clinical chemistry.

421. Pathophysiology and Laboratory Diagnosis (Laboratory). (4:0:12) Prerequisite: concurrent enrollment in Mcbio 420.

423. Pathogenesis of Infectious Diseases. (3:3:0) Prerequisite: Mcbio 402, 403.

Microbial virulence mechanisms, host defense processes, and pathogenesis of infectious disease.

425. Molecular Genetics of Prokaryotes. (3:3:0) Prerequisite: Mcbio 230, 351, Chem 481.

Molecular basis of genetics of bacteria and bacteriophages, including mechanisms of DNA transfer, uptake, recombination, replication, and mutation.

430. Molecular Cell Biology. (3:3:0) Prerequisite: Mcbio 230 or Zool 373.

Emphasizes molecular genetics, cell biology, and developmental biology. For bioscience majors.

441. Molecular Biology of the Gene. (3:3:0) Prerequisite: Mcbio 230, 351, 425, Chem 351, 352.

Molecular biology of gene structure and expression in prokaryotic and eukaryotic organisms.

442. Molecular Biology Laboratory. (2:0:6)

Laboratory to accompany Mcbio 441.

451. Bacterial Physiology. (3:3:0) Prerequisite: Mcbio 351, Chem 352.

Principles of bacterial physiology, including structure-function relationships and biochemical processes. Unique aspects of prokaryotic metabolism.

465. Advanced Laboratory Methods. (2:0:6) Prerequisite: Mcbio 365, 402, 404.

Experimental methodology in immunology and virology. Investigative approach to experimental microbiology.

471. Industrial Applications of Microbiology. (3:3:0) Prerequisite: Mcbio 351.

Commercial applications of microbial processes, quality control systems, scale-up and production line procedures, genetic manipulation of microbes, fermentations and bioassays with industrial applications.

481. History of Microbiology. (1:1:0) Prerequisite: Mcbio 351.

491R. Selections in Critical Literature. (1:1:0 ea.) Prerequisite: senior status.

495R. Special Problems. (1–4:Arr.:Arr. ea.) Prerequisite: department's consent.

Individualized undergraduate research experience.

499R. Senior Honors Thesis. (1–3:0:Arr. ea.) Prerequisite: topic to be cleared with Honors Program and Department of Microbiology.



500-Level Graduate Courses (available to advanced undergraduates)

511. Selected Readings in Immunology. (1:1:0) Prerequisite: Mcbio 402 or equivalent.

Current literature in immunology.

512. Selected Readings in Viral Pathogenesis. (1:1:0) Prerequisite: Mcbio 404 or equivalent.

Current literature in viral pathogenesis.

516. Selected Readings in Emerging Diseases. (2:2:0) Prerequisite: Mcbio 403; 404 or 417; or equivalents.

Factors and mechanisms of emerging and reemerging infectious diseases.

518. Selected Readings in Special Pathogens. (2:2:0) Prerequisite: Mcbio 403; or equivalent.

Current literature dealing with special pathogens.

519. Selected Readings in DNA Diagnostics. (2:2:0) Prerequisite: Mcbio 403 or equivalents.

Current readings in the molecular identification of relationship cases and infectious disease agents.

Graduate Courses

For 600- and 700-level courses, see the BYU 2002–2003 Graduate Catalog.



Microbiology Faculty

Professors

Anderson, Shauna C. (1974) AS, Ricks Coll., 1965; BS, Brigham Young U., 1967; MS, U. of Utah, 1973; PhD, U. of Washington, 1984.

Harker, Alan R. (1994) BS, PhD, U. of Utah, 1976, 1982.

Jensen, James B. (1989) BS, MS, Brigham Young U., 1970, 1972; PhD, Auburn U., 1976.

Johnson, F. Brent (1972) BS, MS, PhD, Brigham Young U., 1966, 1967, 1970.

Leavitt, Ronald W. (1977) BA, U. of California, Riverside, 1967; MS, U. of Illinois, 1969; PhD, U. of California, San Diego, 1975.

Murray, Byron K. (1983) AS, Ricks Coll., 1964; BS, MS, PhD, Brigham Young U., 1966, 1969, 1971.

Nielsen, Brent L. (2000) BS, Brigham Young U., 1980; PhD, Oregon State U., 1985.

O'Neill, Kim L. (1992) BSc, DPhil, New U. of Ulster, Northern Ireland, 1984, 1986.

Woodward, Scott R. (1989) BS, PhD, Utah State U., 1980, 1983.

Associate Professors

Burton, Gregory F. (1997) BS, U. of Utah, 1975; MS, Brigham Young U., 1985; PhD, Medical Coll. of Virginia, Virginia Commonwealth U., 1989.

McCleary, William R. (1995) BS, Brigham Young U., 1982; PhD, U. of California, Berkeley, 1990.

Robison, Richard A. (1991) BS, MS, PhD, Brigham Young U., 1978, 1980, 1988.

Associate Teaching Professors

Breakwell, Donald P. (2001) BS, Brigham Young U., 1986; MS, PhD, Purdue U., 1988, 1992.

Cockayne, Susan (1982) BS, MS, U. of Utah, 1972, 1979; PhD, Brigham Young U., 1990.

Part-time Faculty

Gordon, Jan
Hodson, Kristine
Millington, Lara
Poulsen, Keila
Seeley, Deborah

Adjunct Assistant Professors

Frame, P. Jackson

Adjunct Clinical Professors

Freestone, Lovell, Thorn, Urie

Adjunct Clinical Instructors

T. Jackson, Talbot, Zern

Laboratory Support Services

Lee, John D. (1972) BS, MS, Brigham Young U., 1972, 1976.

Emeriti

Beck, Jay V. (1951) BA, MA, Brigham Young U., 1933, 1936; PhD, U. of California, Berkeley, 1940.

Bradshaw, Willard H. (1961) BS, MS, Brigham Young U., 1952, 1953; PhD, U. of California, Berkeley, 1957.

Donaldson, David M. (1955) BS, MS, PhD, U. of Utah, 1950, 1952, 1954.

Jensen, Marcus M. (1969) BS, MS, Utah State U., 1952, 1954; PhD, U. of California, Los Angeles, 1961.

North, James A. (1965) BS, MS, Brigham Young U., 1958, 1960; PhD, U. of Utah, 1964.

Sagers, Richard D. (1958) BS, MS, Brigham Young U., 1954, 1955; PhD, U. of Illinois, 1958.

Wright, Donald N. (1969) BS, U. of Utah, 1958; PhD, Iowa State U. of Science and Technology, 1964.






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